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چکیده
Atorvastatin Atorvastatin belongs to the category of statins, which inhibits 3-hydroxy-3-methylglutarylcoenzyme A (HMG-CoA) reductase. Synthesis of mevalonic acid is impeded, which is a ratelimiting step in cholesterol biosynthesis. This results in a decrease in intracellular cholesterol leading to an increase in the number of synthesis of LDL receptors and increased clearance of LDL cholesterol in plasma. HMG-CoA reductase inhibitors may also lower plasma cholesterol levels by decreasing hepatic production of VLDL and LDL cholesterol.
منابع مشابه
Evaluation of antibiotic administration for the treatment of acute pediatric diarrhea, Besat Hospital, Sanandaj, 2016
Background: Excessive and irrational use of antibiotics in the treatment of acute diarrhea has caused increased resistance to these medications. It is well defined that most cases of diarrhea in children do not require the use of antibiotics. This study was aimed to determine the status of antibiotic administration for treatment of acute diarrhea in children younger than five years. All who adm...
متن کاملPredisposing Factors for Methadone Poisoning in Children Hospitalized at Kerman Afzalipour Hospital, Iran
Background: Methadone is a synthetic opioid that has been used to relieve severe pain in addiction withdrawal. Unfortunately, due to non-standard supply and storage, the incidence of poisoning and deaths caused by this drug is increasing daily. The purpose of this study was to determine the underlying causes of methadone poisoning in children admitted to Kerman Afzalipour Hospital, Kerman Unive...
متن کاملبررسی وضعیت ثبت اطلاعات در پرونده های بیمارستان های آموزشی دانشگاه علوم پزشکی همدان در سال 1388
Introduction & Objectives: Hospital records are representative evidences of medical team activities. In this study, we analyzed hospital records in Hamadan teaching hospitals to find out the problem extent and possible solutions for the problem. Materials & Methods: In a cross-sectional study, hospital records from teaching hospitals were gathered and put in check lists. We used convenient s...
متن کاملThe Comparison of Microbial Contamination of Work Desks in Official Building of Mashad University of Medical Sciences with that in Central Laboratory of Imam Reza Hospital of Mashhad
Abstract Background and objectives: Pathogens can be transferred via the hands of the personnel not only to themselves but also to their families or to the patient causing infection especially nosocomial infections. Microbial contamination of hand is caused by contact with patients and their environments or usual devices in the workplace. It seems that contamination of computer devices and hand...
متن کاملA Logistic Regression Analysis of Predictors for Asthma Hospital Re-admissions
In order to identify the risk factors (predictors) of re-hospitalisation for high-risk asthmatic patients, a retrospective logistic regression analysis describing the relationship between the probability of re-admission and possible predictors in hospitalised asthmatics, aged over 5 years, between 1994-1998, was designed. Study setting was a district general hospital in the West Yorkshire, UK. ...
متن کاملO12: Excessive Daytime Sleepiness, Dozing at the Wheel and Road Safety
It has been documented that nearly 25-30% of automobile collisions are potentially associated with driving fatigue. We have little control over sleep propensity when chronically sleep-deprived or suffer from an underlying sleep insufficiency. Drowsy driving is not only a personal but also a public hazard and commercial drivers with alternate shifts are critically at risk. People on monotonous d...
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تاریخ انتشار 2007